Colin Clive

After recovering from injuries sustained in the mob attack upon himself and his creation, Dr. Frankenstein falls under the control of his former mentor, Dr. Pretorius, who insists the now-chastened doctor resume his experiments in creating new life. Meanwhile, the Monster remains on the run from those who wish to destroy him without understanding that his intentions are generally good despite his lack of socialization and self-control.

Dr. Henry Frankenstein attempts to create life by assembling a creature from body parts of the deceased. Aided by his loyal misshapen assistant, Fritz, Frankenstein succeeds in animating his monster, but, confused and traumatized, it escapes into the countryside and begins to wreak havoc. Frankenstein searches for the elusive being and eventually must confront his tormented creation.